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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e701897ccd4ed216519610bc4c50f72e0c2510a64ed2515d2653f77dd8a74f4' 
  AND token = 'BeKObeozcuqnR4LySfIr2/vl6w8Rxhq0V0oTGFQ6JuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}