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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f2f6b70d7fed82b40219e4f3f05f318abd781b59d01f707697c9c567688b0c' 
  AND token = 'AvZLT3D32yWYXD2MF4yczbczrHE02L9UjyLprb1Ci10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}