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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af42e3af0478a8b9387e3ebabe4dab83317ed50ab955b1668d5bbee5a2f4d0a5' 
  AND token = 'wj+pcf0RKaGJEGS75pUS9pz9K5T2x6iPOhqQVBmgI4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}