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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a992f890bc5cb25fa1a34ee3bcbf448750c55a4f67e2226ae1a71e19c3dfa176' 
  AND token = 'VQvUz1JfcrDEBcPwczA+yoHipSODgC5RrroyjbV/neM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}