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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c0acc1f7a295c3825f3b61dd35a5e5df5730a68a947f4b97036a2aa3ba7d54e' 
  AND token = 'vbOTBWchP0ssMtD469gV12XIKAbnsw593Qw3UarmoXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}