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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295106b7e353626b2bf86a8e26b09c3e827b3f3d91110b9f6588f66fa06068b7' 
  AND token = '74E3uBC/o0DsPRa1NwQOa4uQOOV2MEG2RQDVzBdbBrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}