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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62bef96cab34e45592e6016011e539dd36d719a636b3887ae6151fcd3170c030' 
  AND token = 'Ez4uHcUwUMIiZcHS26TTZrysBs+LzoFw82axxsuCCtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}