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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422e0ead7136ef591a502e2bfa625aedef377483df459e3fcc181a5c7b22383d' 
  AND token = 'kQuPf2y+rqM43Ph7EnLtaEb9mBph0i5o3iHM/Lsb70o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}