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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6d66ffb2a66d2e4c2e4ac3b8853272b50466239f98304a2a17f85185ec63b15' 
  AND token = 'opO7tL7rOVcSOHEHJQW6gStscJPRI5dVtFBwkrtAorE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}