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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e632db0a5de5dbe71bf6d41553288cb77bacb445b0dacbc54e3f179e92cb5af4' 
  AND token = 'tFtqLo0Hw+yX+m7vDslEBuRuen4X0kI0+/vy0qzkT5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}