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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0d3a4d6462cde6ec9ffc492fd6164b605ca17d233c70b4d6e692edb2348cf86' 
  AND token = 'smdiaonetw8uGK41+sm5yvQN5EGCcJIxdvNPCEoMSFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}