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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04e000defbf9d234531b6d57e208f9af0efc3ef7cdaed0e38d36837bd17a429c' 
  AND token = 'dNQ03dqNy+ixYZhAqDm3xJzD+6lVfY7DL+bxDwqzC2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}