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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ced606d9c5851f303987764da847dac48130e374b8e844155e23bd6ad4a9cc' 
  AND token = 'CcQreoDJBzsIT2WNb8y6hS1oVbtJ5IwUyRT2RSgkz4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}