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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3010c7e6bf2e982e49f079bc233aea2260e1484c34623b079eb27a28d4b4ce7' 
  AND token = 'oL4RgbxesVbHlrvYVgk9q8LXxPDYpzmGYh5ZZbScZUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}