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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3f409d0a0bb1f0595c9c5ddb78ee2f17c6fd6b2a17e061c997f51dd7f7e0149' 
  AND token = 'LuVfAWfdaCpVGYFWtUFbzjan0qx/KV6P3wBdM8kINqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}