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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df029ca77f06fe3b2d69c0d10b47fbd496ec5e08e45c456e6125bbbd2021b9c2' 
  AND token = 'HfhyT14csIsbBXH155iNQYYAdzsxgWRXyfKME9RPuRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}