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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a25d20768ef0cd9593773250af4c38c3b43667b32b4cb6619dd3cc80d4e3c93' 
  AND token = 'WwD2jR9YfJC4MtfNT7+yooSzrMsLeYP4VW5LMgdkz5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}