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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66bb67a50a321b029735f39d37c104f0a1533b0a929e2ae6a4236d2c45960a06' 
  AND token = 'cJHmSW7KINED9fsipG9igEmVnmDXWw9oDjCRX3/+zEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}