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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b53b26c54da6e62b9af3bbcdfba87d3ee0264e3d5c58bdaf08edfaa101b0f94' 
  AND token = '1zjV8BHkt7EF/pBSr2yZdiHVtluTNPsJ0ClW346To7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}