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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c5bbaf259f61de8f1d0ee10959a970eeff267321af56e073d96195930bee41' 
  AND token = 'HjZDJ0RGd8Bbd2t/QFIZCT+GCUdLH0KpN7rtq2uvZcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}