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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd00227a2d947ba6eea938f6223a39991601bc866226b024c1a6310b5d1693007' 
  AND token = 't2XQTLQVh5693L1qvVjKOCF3uMm/nBe2hkXgAD0O3d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}