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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39cb3f083491a4b40615b73ad20067e46ffcbc3f86d7f0dbd858695200c5ff4a' 
  AND token = '+DtDMh6KROmq7WyxotcPlVo1bjoZrvtGNj4vx6sU4lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}