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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d17dbfc8a0ea5be5c54b502ad7c68ee038a04bdb0d9abb2b6a579019b13ee4c' 
  AND token = 'MUaR4R9keTXmsyPypnDgcoW7jQE6IZ6k5QmB9+NLsbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}