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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef22e4ffc171892dece30347e02caf505fa7235791115d339f656e99d774d66' 
  AND token = 'l9NTf8RNNRLoy9UMs6fzJOkCtAhA10YvEGqe7zxMD50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}