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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6591e34e34693508374c1497c5966d3807c1a14ec677da5082d673023d89ef8' 
  AND token = 'cZJHEgQZ528kWMbr3Qh4FFirB8jSbXNlKYaJ/bDgRGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}