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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84fa22447c4a157cba5a00bc21fe4d5fe7854de58c4621ed1a595a69b4d8c7b4' 
  AND token = 'hSFUjiYE4N+TW35GoHlFVygz3fsVDAHt2E/DhE2AWvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}