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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc2e5ad18eb953bf2a7495a3db1530df6a240b7b7a9689fd4dc341bcc56f3f36' 
  AND token = 'ZbEW54quNOqiURs5mb+uM/P1ofc98vpYTdeB8pPRSqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}