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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '30f90ac7c08e4f2c99e6f27485545a9999613041a48decf8410023c44bac5dc5' 
  AND token = 'PxyhSEp5p6wWgkg5B3s7TaolQgKvdFU4bLKq0JL4TFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}