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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22afeddc2729812106cfd774e9b84101d8f98e1f341ee0ba98e0732f8385124' 
  AND token = '1nSznRJnZ0VSj0dU3zYc+XPGmFFXozJK7xAcDX5jY3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}