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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3b6e449d9ae946b19fb2000de20352d979617002a3f513e4dc6b57a736d8f3' 
  AND token = 'vf+HUSOXAzo7Izk4Qd+rVYPJ2yfyhzM9ynDXlHVu/lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}