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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75878ba147a3f8f34078c0d37275c083273be6292294c44db7b42598d9e07c5b' 
  AND token = 'iFPZBcduwg/RwvdtkLhcHb43nOUUwUFXHuOAceB8VeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}