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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b53f12c15d3758b07f06e40fef8fe0f9e2d9d19f84d143e11e9c46459b3e58f' 
  AND token = 'KBxtxKSMW5YUc6BneE6xmIZjptPCLRb/qMIzlVar54Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}