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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e356125fe04fdd2a90aa1981305021b01e276dd99e3c1c78b72cdb6d528d0023' 
  AND token = 'lFyo5EXKUDaSKMK3LCip4oR0PDo5Rd0Y39rtkH65TEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}