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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd650349aa87233744ea1189e01d8a7f013cb1ee4bef43a8371bbd8b1508f7533' 
  AND token = 'Iw+Fo5IaMCjxuCZAd51tlJaaYeXERdrBlmuWgYd+qUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}