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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e8f67c35cf4f3e2142d3155c4f4e1756fd0980e9d27f26a26393ee1a749b1a2' 
  AND token = 'dHTDCGnUHZ57UTpbwf05L0P6SJdQUtA84699w6jqiu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}