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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81b87609d2517d9b057b6f668c54985b59784eb0880cbca720551227791c24c' 
  AND token = 'a2+QClT3Z6Zto5ixa8IoBmqU6kzeOMYcMZICWKKtCoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}