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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e016cc1c9b494f4e3377eb2c083457fca09219bd1a45eefbd339ef776427049' 
  AND token = 'YsEyx3ic/xVzgZnuCYyvCOro4EErx4/4UWeoO2/WWco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}