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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b46e77b3c747900511e8174a3747026a01d921c201e39ea8bcf325f2b97af59' 
  AND token = 'mmPDdj6eUXuqQ6UOnZwAh9E5MFvCVMdG18wvfDmOvcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}