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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c055d3316b9a3f2cddd1772d67e6f3cdfafdf6b067d36339ab349804c83b573' 
  AND token = 'N+i68P1W14oXWg9uHyKVlSwKtDgeeswqwgjMXjuKXPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}