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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fddcbacb85a656c72aff73b1b3cae6e0357c6eaf7c7707e60dfb750a204dcef0' 
  AND token = 'ZPynGjx3SOujCG4ZfIl7++h6+6OEmWuoRDoEz+eG4b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}