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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1037cefea8fd6379b0d6a75db8c174220a060237149631d8c07b7c56317bd2' 
  AND token = 'Reizdfk/03A4oa5DtygldZdE6b+TQYgGm5ug1VYWJrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}