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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fadd540b2153836606ca2cd3f50e9594c89259a84cadb7d2221f56ab741cb63d' 
  AND token = 'V+txHvn0NKDX+45w8r93t9IyyroWkl01EXpBeXEjjo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}