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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a014e7801ae427381855f524e87e38d09ccda8ce7f197372a0c9b50e479ed0' 
  AND token = 'lO6bGRtzx9qjCPOFJVkNPlbDiXHQC2ECQ5gbFcDlXtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}