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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9081ee63983273a1031c63a1f2723a0b736a0f781ee4aad0dd67850b42e72c48' 
  AND token = 'WJrUaQJC1EpViQiBaFkRwfJNRqCZvW+7lNzvxJWBh3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}