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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9220ac7ecff58dbeb9f096df1348eb01b794fa2fa96545d2ca64eb678d4a920' 
  AND token = 'RbnIzsLmixx+8EqB6k2N4wKX25ZAQCaFC797DimwOIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}