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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37904160cb9d333e8cc4a0242aa446f0d14a7217f334638ea738ed5b9c2d1c51' 
  AND token = 'uDPUodungmWUyf9KuhdmUxKJWq2hUhf7CyW0Qel9sOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}