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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a8f43fb7565e3f8612d5dfc4c8105ab7b7dc25ef96fd6d260e233006127154' 
  AND token = 'vuMppB4sr9jV3e11Y2WgsTA7eqTwCcfbv/RQ7ZBHqD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}