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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33981519ff29372ef511e3ee22c66c72f1ce70e0f350998793426fcf3c9f3f5' 
  AND token = 'IaR4iTj5fR7cTxSQy319I6tty5m1gIRmlBFY6UP1STg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}