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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09fffba7424785d1870912b603b499bf66f6c66a17148994591ae0daaf3634e2' 
  AND token = 'lr1aH0JGb/uMQLNQbMtoP8YXP5yIHFHmrvE72Xsav0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}