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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25efc832efef213b25442a2640e0a1cf4894b3c672bd3bf7e326c960ebf32494' 
  AND token = 'w8mp5fym8mOCeEyHC7yfSjVEyI8b5Qsy0JPd5JHFflg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}